

Although current reports indicate that NDM-1 does not hydrolyze monobactams, most of NDM-1-carrying strains also express enzymes that could hydrolyze monobactams, making NDM-1-producers very difficult to control. It confers resistance to a broad-spectrum of β-lactams, including carbapenems, which are the mainstream treatment for antibiotic-resistant bacterial infections. The emerging New Delhi metallo-β-lactamase (NDM-1), an acquired class B carbapenemase that was first clinically detected in a patient at a hospital in New Delhi, India, has brought up worldwide public attention again –. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.Īntimicrobial resistance is a growing global challenge to human health. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This work was supported by Internal Funding of Guang'anmen Hospital (Grant# 2011S242) and Beijing You'an Project for Liver diseases and AIDS (Grant# JYAN-2011-064). Received: JanuAccepted: Published: June 10, 2013Ĭopyright: © 2013 Liu et al. PLoS ONE 8(6):Įditor: Qijing Zhang, Iowa State University, United States of America (2013) Identification and Characterization of the First Escherichia coli Strain Carrying NDM-1 Gene in China. The findings of this study raise attention to the emergence and spread of NDM-1-carrying Enterobacteriaceae in China.Ĭitation: Liu Z, Li W, Wang J, Pan J, Sun S, Yu Y, et al. Genetic analysis revealed that the region flanking bla NDM-1 was very similar to previously identified NDM-positive Acinetobacter spp. Analysis of genetic environment shows complex transposon-like structures surrounding the bla NDM-1 gene. BJ01 was identified as a new sequence type, ST224, by multilocus sequence typing. coli EC600 and DH5α in both plasmid conjugation experiments and plasmid transformation tests. bla NDM-1, bla CTX-M-57, and bla TEM-1 were identified in the isolate. The isolate is highly resistant to all tested antimicrobials except polymyxin. In this study, we identified the first confirmed clinical isolate of Escherichia coli BJ01 harboring bla NDM-1 in China. For more information about Oracle (NYSE:ORCL), visit Delhi metallo-β-lactamase-1 (NDM-1), an acquired class B carbapenemase, is a significant clinical threat due to its extended hydrolysis of β-lactams including carbapenems. Oracle offers a comprehensive and fully integrated stack of cloud applications and platform services. My Oracle Support provides customers with access to over a million knowledge articles and a vibrant support community of peers and Oracle experts.
NDM ID FULL
To view full details, sign in with your My Oracle Support account.ĭon't have a My Oracle Support account? Click to get started! Locator INVALID OBJECTS: SEMCONTEXTINDEXMETHODS - INVALID - TYPE BODY Changes Locator INVALID OBJECTS: SPARQL_MAX_VC - INVALID - TYPE BODY Locator INVALID OBJECTS: SPARQL_MIN_VC - INVALID - TYPE BODY Locator INVALID OBJECTS: SPARQL_GROUP_CONCAT_VC - INVALID - TYPE BODY

Locator INVALID OBJECTS: SPARQL_MAX - INVALID - TYPE BODY Locator INVALID OBJECTS: SPARQL_MIN - INVALID - TYPE BODY Locator INVALID OBJECTS: SPARQL_SERVICE_IMPL_T - INVALID - TYPE BODY Locator INVALID OBJECTS: RDF_MATCH_IMPL_T - INVALID - TYPE BODY Locator INVALID OBJECTS: SDO_RDF_TRIPLE_S - INVALID - TYPE BODY Locator INVALID OBJECTS: SDO_RDF_TERM - INVALID - TYPE BODY Locator INVALID OBJECTS: SDO_SEM_INFERENCE - INVALID - PACKAGE Locator INVALID OBJECTS: RDF_APIS - INVALID - PACKAGE Locator INVALID OBJECTS: NDM_RESET_ID_GENERATOR - INVALID - FUNCTION Invalid MDSYS objects are found in the database even when SDO is in status REMOVED. Information in this document applies to any platform. Oracle Database - Enterprise Edition - Version 12.2.0.1 to 12.2.0.1 Oracle Spatial and Graph - Version 11.2.0.4 and later Invalid MDSYS objects after running mddins.sql to keep Locator option on 12.2.0.1
